Advanced Clinicals, Retinol Serum, Anti-Wrinkle, 1.75 fl oz (52 ml)



Total Score
The total score is calculated by our algorithm, that learns latest available scientific research, and uses products ingredients, and other data, to estimate the efficiency and safety of this product.
Community reviews
Combined average by the 0 reviews from Amazon US and 40100 from iHerb US
Ingredients Check
Using scientific studies our algorithm provides estimates for every ingredients in this product
Great
This group contains ingredients that were scientifically shown to work best for Anti-Aging Creams
Good
This group contains ingredients that has scientifically shown significant improvements when used in Anti-Aging Creams
Caution
This group contains ingredients that were scientifically shown to cause irritation, or similar, when used in Anti-Aging Creams
Skin type
Based on the ingredients list, our algorithm can make science-based estimates for every skin type.
- The presence of heavy emollients like isopropyl myristate and squalane may lead to increased oiliness for oily skin types.Oily
- While some emollients may benefit dry areas, the overall formulation may be too heavy for the oily regions of combination skin.Combination
- The inclusion of humectants like glycerin and soothing ingredients such as aloe vera and various extracts makes it suitable for hydrating dry skin.Dry
Ingredients content
What science-proven ingredients for Anti-Aging Creams are included in this product.
- Contains retinol, a form of vitamin A known for its anti-aging benefits.Retinoids
- Includes various antioxidants like tocopherol, green tea extract, and rosemary leaf extract to protect skin from free radicals.Antioxidants
- Does not contain peptides known for their skin-firming benefits.Peptides
- Does not contain hyaluronic acid known for its superior hydration properties.Hyaluronic Acid
- Does not contain AHAs known for exfoliating and skin-brightening properties.Alpha Hydroxy Acids (AHAs)
- Does not contain BHA like salicylic acid known for exfoliation and treating acne.Beta Hydroxy Acid (BHA)
- Does not contain niacinamide known for its calming and brightening effects.Niacinamide
- Does not contain growth factors known for their anti-aging and skin-repairing properties.Growth Factors
- Does not contain sunscreen agents, so additional sun protection is needed during the day.Sunscreen Agents
Other estimates
What common functions ingredients in this product can contribute to promoting
- Contains hydrating ingredients like glycerin and aloe, but additional moisturizer may be needed for very dry skin.Moisturization
- Beneficial for all skin types, does not feel greasy or heavy.Feel on the skin
- Contains fragrance which may be a concern for sensitive skin.Fragrance
Ingredients Review
Great
This group contains ingredients that were scientifically shown to work best for Anti-Aging Creams
- 10/10Aqua
Water is essential for hydrating the skin, maintaining its moisture balance, and ensuring the efficacy of other active ingredients in anti-aging creams.
- 10/10Glycerin
Glycerin is a perfect ingredient for anti-aging creams, as it is a powerful humectant that deeply hydrates the skin, improves elasticity, and helps reduce the appearance of fine lines and wrinkles.
- 10/10Retinol
Retinol is highly effective in reducing fine lines, wrinkles, and signs of aging, making it an excellent choice for anti-aging creams.
- 8/10Squalane
Squalane is a highly moisturizing ingredient that helps to hydrate and plump the skin, reducing the appearance of fine lines and improving skin texture in anti-aging creams.
- 8/10Sunflower Seed Oil
Sunflower seed oil is rich in antioxidants and vitamin E, which help to moisturize, protect against environmental damage, and promote anti-aging effects.
Good
This group contains ingredients that has scientifically shown significant improvements when used in Anti-Aging Creams
- 6/10Isopropyl Myristate
Isopropyl myristate can enhance penetration of other active ingredients in anti-aging creams, but may cause clogged pores in some individuals if used in high concentrations.
- 7/10Ethylhexyl Olivate
Ethylhexyl olivate is a lightweight emollient that helps to improve the texture and feel of anti-aging creams without feeling greasy.
- 8/10Cetearyl Alcohol
Cetearyl alcohol is a fatty alcohol that provides emollient and hydrating properties, beneficial for anti-aging creams, but it may cause slight irritation in some people.
- 7/10Pyrus Malus (apple) Fruit Extract
Apple fruit extract contains antioxidants and nourishing properties beneficial for anti-aging formulations, although its effectiveness may vary depending on the specific product formulation.
- 8/10Aloe Vera Extract
Aloe vera extract is hydrating, soothing, and can help improve skin elasticity, making it a good choice for anti-aging creams.
- 8/10Propanediol
Propanediol is a versatile ingredient that can help improve the spreadability and texture of anti-aging creams while providing hydration and enhancing the absorption of other active ingredients.
- 7/10Avena Sativa Kernel Extract
Avena Sativa Kernel Extract is known for its soothing and anti-inflammatory properties, making it beneficial in reducing skin irritation and providing moisture which are important for anti-aging products.
- 8/10Tocopherol
Tocopherol, a form of vitamin E, has antioxidant properties that can help protect the skin from damage and maintain its youthful appearance, making it good for anti-aging creams.
- 7/10Camellia Sinensis Leaf Extract
Camellia Sinensis Leaf Extract has antioxidant properties that can help combat the signs of aging by protecting the skin from environmental damage.
- 7/10Oryza Sativa (rice) Bran Extract
Rice bran extract contains antioxidants and vitamins that help improve skin tone and texture, making it beneficial in anti-aging formulations.
- 7/10Orange Peel Extract
Orange peel extract is rich in antioxidants and vitamin C, which can help brighten and even out skin tone, making it a good addition to anti-aging creams.
- 7/10Helianthus Annuus (sunflower) Extract
Helianthus Annuus (Sunflower) Extract is rich in antioxidants, which can help protect the skin from environmental damage and promote overall skin health, making it a good ingredient for anti-aging creams.
- 7/10Humulus Lupulus (hops) Extract
Hops extract is rich in antioxidants, which can help fight free radicals and promote skin health, making it a good ingredient for anti-aging creams.
- 7/10Rosemary Extract
Rosemary extract has antioxidant and anti-inflammatory properties that can help reduce signs of aging, boost circulation, and improve skin's overall health.
- 7/10Ammonium Acryloyldimethyltaurate/vp Copolymer
Ammonium acryloyldimethyltaurate/VP copolymer is a good ingredient for anti-aging creams as it helps to create a smooth texture, improve product stability, and enhance skin feel.
- 7/10Phenoxyethanol
Phenoxyethanol is a safe and effective preservative that helps maintain the shelf life of anti-aging creams, but may cause allergic reactions in some individuals.
- 8/10Caprylyl Glycol, Ethylhexylglycerin
Caprylyl Glycol and Ethylhexylglycerin are gentle preservatives with moisturizing properties suitable for anti-aging creams, helping to keep the formula stable and skin hydrated.
- 8/10Hexylene Glycol
Hexylene glycol is a solvent that helps in improving the texture of anti-aging creams and enhances the absorption of other active ingredients, making it good for this product type.
- 7/10Copernicia Cerifera (carnauba) Wax
Carnauba wax offers emollient and protective properties, making it suitable for anti-aging creams, but it might be too heavy for some individuals or cause pore blockages.
- 7/10Tetrasodium Glutamate Diacetate
Tetrasodium glutamate diacetate is a chelating agent that helps improve the stability and efficacy of skincare formulations, suitable for anti-aging creams.
- 7/101,2-hexanediol
1,2-hexanediol is a humectant and solvent that can improve the texture and feel of anti-aging creams.
- 7/10Xanthan Gum
Xanthan Gum can help improve the texture and consistency of anti-aging creams without causing irritation, but may not provide direct anti-aging benefits.
- 8/10Ethyl Ferulate
Ethyl Ferulate is a potent antioxidant and helps protect the skin from free radical damage, making it beneficial in anti-aging creams.
- 7/10Limonene
Limonene is a natural antioxidant that can help with anti-aging by protecting the skin from free radical damage and promoting collagen production.
Caution
This group contains ingredients that were scientifically shown to cause irritation, or similar, when used in Anti-Aging Creams
- 2/10Cyamopsis Tetragonoloba (guar) Gum
Guar gum is more commonly used as a thickening agent rather than an active anti-aging ingredient, so it may not provide optimal benefits for anti-aging creams.
- 4/10Polysorbate 20
Polysorbate 20 may not be the best choice for anti-aging creams as it may not provide significant anti-aging benefits and could potentially cause skin irritation for some individuals.
- 10/10Parfum/fragrance
Fragrance or parfum can be irritating to the skin, especially with anti-aging products that have active ingredients that can make the skin more sensitive.
Product overview
Description (by the manufacturer)
- Antioxidant Green Tea
- Rejuvenating Anti-Wrinkle Concentrate
- Encapsulated Retinol Effectively Fights the Look of Wrinkles
- Nourishing Aloe Vera and Green Tea
- Glycerin Attracts Moisture to the Skin for a Plump Appearance
- Aloe Vera Defends Against Visible Redness and Irritation
- Antioxidant Green Tea Guards Against Environmental Damage
- Retinol Corrects the Looks of Deep Wrinkles and Jowls
- Visibly Replenishes Volume to Mature Skin
- Improves the Look of Sagging, Sun Damaged Skin
Benefits
- This anti-aging Retinol serum is professionally formulated to reveal fresh, soft skin
- Safe for daily use
- Diminishes the look of deep wrinkles and sun damage
Attributes
- Fast absorbing: this serum has a lightweight texture that absorbs quickly into the skin, allowing for easy application and layering with other skincare products
- This serum is gentle due to its soothing and calming ingredients, minimizing the appearance of irritation and providing a comfortable experience for sensitive skin
Technology
- Advanced Clinicals Retinol Serum uses encapsulated Retinol for ultimate efficiency
- Replenishing anti-aging ingredients visibly restore volume to areas prone to sagging and wrinkles. Softens the look of harsh lines and deep wrinkles
- Promotes a more youthful looking skin tone by concealing the appearance of sun damage
Results
- Instantly: Some tightness, flushing or redness may occur when you first use Retinol. This is normal and means it's working. Use an additional moisturizer or reduce frequency to every other night until skin adjusts to renewal ingredients
- Nightly use: The perfect overnight treatment. Wake up daily to visibly softened wrinkles and smoother looking skin
- Dramatically reduces appearance of wrinkles, sagging pores and sun spots

Suggested Use (by the manufacturer)
After cleansing, allow skin to dry completely. Gently pat Retinol Serum over face, focusing on problem areas. Wipe any excess on tops of hand, as they are often exposed to sun damage. Allow several minutes to absorb. Use every night before bed. Redness, tightness or flushing may occur. This is normal and means the product is working. If irritation persists, reduce frequency of use to every other night. Gradually increase use to every night as tolerated. As with any product, if rash develops, discontinue use and consult a doctor.
General advice for using Anti-Aging Creams
Read more science-based information about Anti-Aging Creams: how to use, how to choose, and moreDisclaimer
Questions and Answers
What are anti-aging creams?
Can anti-aging creams get rid of age spots?
Are there any age restrictions for using anti-aging creams?
Subscribe to our newsletter
Get all the latest posts delivered straight to your inbox.

Our goal is to empower healthy skincare choices by bringing the science to the public. By analyzing the latest scientific research we created TheSkincare Algorithm, which is providing guidance and reviews for skincare products.
Unauthorized use and/or duplication of this material without express and written permission from this site’s author and/or owner is strictly prohibited.
Excerpts and links may be used, provided that full and clear credit is given to theskincare.io with appropriate and specific direction to the original content.