Detailed answer

While some individuals may report improvement in melasma after undergoing intravenous glutathione therapy, no scientific studies have been conducted to prove its effectiveness. Melasma is a complex skin condition that is influenced by various factors like hormones, sun exposure, and genetics. Currently, topical treatments such as hydroquinone, tretinoin, and corticosteroids, along with sun protection, are the most commonly recommended approaches to manage melasma. It is always advisable to consult with a dermatologist or skincare professional to determine the most appropriate treatment options for melasma.