Detailed answer

Immunomodulators, such as topical calcineurin inhibitors, are commonly used in eczema treatment. These medications help regulate the immune system's inflammatory response, reducing redness, itching, and flares associated with eczema. They work by suppressing the activity of immune cells in the affected skin, ultimately improving the skin's condition and reducing the need for other therapies. However, it's important to note that these medications should be used under medical supervision and for short periods due to potential long-term safety concerns. Additionally, immunomodulators are more commonly recommended for moderate to severe eczema cases when other topical treatments have not provided adequate relief.