Detailed answer

In severe cases of eczema, the immune system is overactive, leading to chronic inflammation and intense itching. Immunosuppressants help alleviate the symptoms by suppressing the immune response, thereby reducing inflammation. They work by inhibiting the activity of certain immune cells and the release of inflammatory substances. By targeting the underlying immune dysfunction, immunosuppressants can provide relief and improve the overall condition of the skin. However, it is important to note that the use of immunosuppressants may have potential side effects and should be closely monitored by a healthcare professional. They are typically prescribed as a second-line treatment option when other topical or systemic medications have been ineffective in managing severe eczema symptoms.